Composite Scaffolds for Large Bone Defects

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Abstract

This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

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Daskalakis, E., Aslan, E., Liu, F., Cooper, G., Weightman, A., Koç, B., … Bartolo, P. J. (2020). Composite Scaffolds for Large Bone Defects. In Lecture Notes in Mechanical Engineering (pp. 250–257). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-030-29041-2_31

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