Immunoglobulin A (IgA) nephropathy (IgAN) was first described in 1968 by Berger and Hinglais [1] and is now recognized as a distinct clinicopathologic entity with a higher frequency worldwide than any other primary glomerulopathy [2]. It was initially considered a benign condition, but extended follow-up of patients indicated that 20–50 % of adults would ultimately progress to end-stage renal failure [2, 3]. Likewise, the favorable prognosis initially attributed to children with IgAN must be questioned in the light of studies [4–8].
CITATION STYLE
Nakanishi, K., & Yoshikawa, N. (2015). Immunoglobulin a nephropathies in children (includes HSP). In Pediatric Nephrology, Seventh Edition (pp. 983–1033). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-43596-0_28
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