Screening mammalian cells on a hydrogel: Functionalized small molecule microarray

Abstract

Mammalian cell-based microarray technology has gained wide attention,for its plethora of promising applications. The platform is able to provide simultaneous information on multiple parameters for a given target,or even multiple target proteins,in a complex biological system. Here we describe the preparation of mammalian cell-based microarrays using selectively captured of human prostate cancer cells (PC-3). This platform was then used in controlled drug release and measuring the associated drug effects on these cancer cells.