Phytochemical screening and antidiabetic activity of different leaf extracts from lotus (Nelumbo Nucifera gaertn.) in streptozotocin induced mice

Abstract

Objective: The present study is to evaluate the antidiabetic activity of various extract of Lotus (Nelumbo nucifera Gaertn.) leaf using hexane, ethyl acetate, and ethanol organic solvent. Methods: Standard phytochemical screening method and streptozotocin induced diabetic mice. Result: The phytochemical screening showed only ethyl acetate of lotus leaf extract contains the flavonoids. The ethyl acetate lotus leaf extract (dose level 150 mg/kg) showed a significant reduction of the blood glucose. Conclusion: The ethyl acetate extract of lotus leaf (N. nucifera Gaertn.) had the hypoglycemic effect on diabetic induced mice.