Phytochemical analysis and biological evaluation of forsskaolea viridis aerial parts

Abstract

The chemical investigation of the chloroform and ethyl acetate extracts of the aerial parts of Forsskaolea viridis Ehrenb. ex Webb (Family: Urticaceae) led to isolation eight compounds for the first time, from the plant where two phenolic compounds, identified as ρ-coumaric and caffeic acids as well as six flavonoid compounds identified as 5-hydroxy-6,7,3í,4í-tetramethoxy flavone, chrysoeriol, acacetin, chrysoeriol-7-O-fl-D-glucoside, kaempferol-3-O-(2″-O-E-p-coumaroyl)-fl-D-glucoside and isovetixin. The chemical structure of the isolated compounds was established by spectroscopic methods including UV, MS, 1H-NMR, and 13C-NMR. Antimicrobial, antioxidant and cytotoxic activities of the ethyl acetate and chloroform extracts were evaluated. The ethyl acetate extract exhibited strong antimicrobial activity (12-30 mm) against the tested strains. The ethyl acetate and chloroform extracts showed fair antioxidant and cytotoxicity.