Accelerator Mass Spectrometry is a mass spectrometric method of detecting long-lived radioisotopes without regard to their decay products or half-life. The technique is normally applied to geochronology, but is also available for bioanalytical tracing. AMS detects isotope concentrations to parts per quadrillion, quantifying labeled biochemicals to attomole levels in milligram-sized samples. Its advantages over non-isotopic and stable isotope labeling methods are reviewed and examples of analytical integrity, sensitivity, specificity, and applicability are provided.
CITATION STYLE
Vogel, J. S., & Turteltaub, K. W. (1998). Accelerator mass spectrometry as a bioanalytical tool for nutritional research. In Advances in Experimental Medicine and Biology (Vol. 445, pp. 397–410). Springer New York LLC. https://doi.org/10.1007/978-1-4899-1959-5_25
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