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Evidence of Clonal Expansion in the Genome of a Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolate from Peru

  • Galarza M
  • Tarazona D
  • Borda V
  • et al.
Genome Announcements (2014) 2(1)
DOI: 10.1128/genomea.00089-14
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Abstract

We report the genome sequence of Mycobacterium tuberculosis INS-MDR from Peru, a multidrug-resistant tuberculosis (MDR-TB) and Latin American-Mediterranean (LAM) lineage strain. Our analysis showed mutations related to drug resistance in the rpoB (D516V), katG (S315T), kasA (G269S), and pncA (Q10R) genes. Our evidence suggests that INS-MDR may be a clonal expansion related to the African strain KZN 1435.

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Galarza, M., Tarazona, D., Borda, V., Agapito, J. C., & Guio, H. (2014). Evidence of Clonal Expansion in the Genome of a Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolate from Peru. Genome Announcements, 2(1). https://doi.org/10.1128/genomea.00089-14

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