Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus

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Abstract

Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.

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Li, S., Mou, Q., Xu, X., Qi, S., & Leung, P. H. M. (2018). Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus. Royal Society Open Science, 5(5). https://doi.org/10.1098/rsos.172466

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