Phytochemical screening and In Vitro Antioxidant potential of Memecylon umbellatum Burm leaf extracts

  • Killedar S
  • Mali S
  • More H
  • et al.
N/ACitations
Citations of this article
15Readers
Mendeley users who have this article in their library.

Abstract

Objective: Different dry extracts of Memecylon umbellatum Burm leaf obtained by various solvents such as petroleum ether, chloroform, ethyl acetate, acetone, methanol and chloroform water (IP) was screened to reap the benefits of its antioxidant and free radical scavenging properties using ascorbic acid as standard antioxidants. Methods: The in vitro free radical scavenging activity was evaluated using diphenyl picryl hydrazyl (DPPH) radical method using various concentrations of dry extract in distilled water (1, 2, 4, 8, 16, 20 μg/ml) against blank with ascorbic acid as a standard in same concentrations. Results: Among the all extracts, Methanol leaf extract has showed higher Antioxidant activity (84.65 ± 0.064 %) having IC 50 Value 11.81 ± 0.033 μg/ml at 20 μg/ml. While, IC 50 value for ascorbic acid was found to be 8.91 ± 0.084 μg/ml. Conclusion: The results clearly indicate that Methanol leaf extract of Memecylon umbellatum is effective in free radical scavenging. So in future, this may emerge as promising natural herbal source of powerful antioxidant.

Cite

CITATION STYLE

APA

Killedar, S. G., Mali, S. S., More, H. N., Nadaf, S. J., Salunkhe, S. S., & Karade, R. S. (2014). Phytochemical screening and In Vitro Antioxidant potential of Memecylon umbellatum Burm leaf extracts. Journal of Drug Delivery and Therapeutics, 4(2). https://doi.org/10.22270/jddt.v4i2.788

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free