Abstract
Artemisinin resistance in Plasmodium falciparum is associated with nonsynonymous mutations in the Kelch 13 (K13) propeller domain. We found that 12.1% (8/66) of clinical P. falciparum isolates from Huye district, Rwanda, exhibited K13 mutations, including R561H, a validated resistance marker. K13 mutations appear to be increasing in this region.
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APA
Bergmann, C., van Loon, W., Habarugira, F., Tacoli, C., Jäger, J. C., Savelsberg, D., … Mockenhaupt, F. P. (2021). Increase in kelch 13 polymorphisms in plasmodium falciparum, southern Rwanda. Emerging Infectious Diseases, 27(1), 294–296. https://doi.org/10.3201/eid2701.203527
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