Surgical management of short bowel syndrome by construction of an isoperistaltic intestinal valve: An experimental study in dogs

Abstract

Objective: To develop of an isoperistaltic invaginated valve for the treatment of short bowel syndrome. Design: Randomised experimental study Setting: University Hospital, Greece. Material: 8 mongrel dogs Intervention: 90% resection of the small bowel, followed by construction of an invaginated valve one month later. Main outcome measures: weight loss, fat excretion in the faeces, radiographic and histological examination of the valve, pressure curve along the valve. Results: Weight loss and steatorrhoea were reversed over a period of 2-3 months without evidence of intestinal obstruction in any of the animals. Conclusions: The construction of an isoperistaltic invaginated valve could be a solution to the management of the short gut syndrome.