Abstract
Novel anti-Helicobacter pylori antibiotics, pyloricidins A, A1, A2, B, C and D, were discovered in the culture broth of two bacilli strains. Pyloricidins selectively inhibited the growth of H. pylori. Pyloricidin B was efficacious in the treatment of gastric infection caused by H. pylori in Mongolian gerbils and may be promising for cure of H. pylori infection as a single agent.
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CITATION STYLE
Nakao, M., Miyagawa, K. I., Nakano, Y., Sakane, T., Tada, M., Nishimura, O., & Fujino, M. (2001). Pyloricidins, novel anti-Helicobacter pylori antibiotics produced by Bacillus sp. I. Taxonomy, fermentation and biological activity. Journal of Antibiotics, 54(11), 926–933. https://doi.org/10.7164/antibiotics.54.926
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