Populations of bone marrow stromal cells (BMSCs, also known as bone marrow-derived "mesenchymal stem cells") contain a subset of cells that are able to recapitulate the formation of a bone/marrow organ (skeletal stem cells, SSCs). The biological properties of BMSC cultures are assessed by a variety of assays, both in vitro and in vivo. Application of these assays in an appropriate fashion provides a great deal of information on the role of BMSCs, and the subset of SSCs, in health and in disease. © 2014 Springer Science+Business Media, LLC.
CITATION STYLE
Robey, P. G., Kuznetsov, S. A., Riminucci, M., & Bianco, P. (2014). Bone marrow stromal cell assays: In vitro and in vivo. Methods in Molecular Biology, 1130, 279–293. https://doi.org/10.1007/978-1-62703-989-5_21
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