Inhibition of protein amyloidosis by glycomaterials

Abstract

In this mini review, the development of glycomaterials for inhibition of protein amyloidosis is described. It has been pointed out that saccharide-protein interactions are related to the amyloidosis but there are few investigations available to clarify the saccharide functions in amyloidosis and to utilize them. We approached amyloidosis with the utilization of saccharide materials in mind. We regard saccharides as an assembly of functional modules and the saccharides were thus reconstructed as materials to utilize them for analysis and inhibition of amyloidosis.