CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies

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Abstract

The CRISPR revolution that began in 2013 has been adopted and embraced by many researchers worldwide, including the mouse molecular genetics community. CRISPR represents one of only a few radical and transformative shifts in transgenic technologies over the past 30 years. This chapter discusses the paradigm shift that CRISPR technology has brought about in the field of mouse genome editing.

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Gurumurthy, C. B., Quadros, R. M., Sato, M., Mashimo, T., Lloyd, K. C. K., & Ohtsuka, M. (2016). CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies. In Genome Editing (pp. 65–77). Springer International Publishing. https://doi.org/10.1007/978-3-319-34148-4_4

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