Effects of nebulized lignocaine on the intraocular pressure responses to tracheal intubation

Abstract

Summary: We have examined the effect of preoperative administration of nebulized lignocaine or saline on the intraocular pressure (IOP) response to tracheal intubation in 20 adults. In the saline group, tracheal intubation was associated with a significant increase in IOP above control and preintubation values (P < 0.01); in the lignocaine group there was no change in IOP following intubation. After intubation, IOP was significantly less in the lignocaine group than in the saline group (P < 0.05). © 1990 British Journal of Anaesthesia.