Introduction

  • Nikles J
  • Mitchell G
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Abstract

N-of-1 trials are multi-cycle within-patient, randomized, double-blind, cross-over comparisons of a drug and placebo (or another drug) using standardized measures of effect. They provide evidence-based information on individual response to treatment and can be used to optimize the chronic disease management of the individual. (PsycINFO Database Record (c) 2019 APA, all rights reserved)

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Nikles, J., & Mitchell, G. (2015). Introduction. In The Essential Guide to N-of-1 Trials in Health (pp. 1–7). Springer Netherlands. https://doi.org/10.1007/978-94-017-7200-6_1

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