Application of high frequency bipolar electrocoagulation LigaSure™ in appendix vermiformis of rabbits with or without acute inflammatory process

Abstract

Purpose: To evaluate the efficacy of the use of LigaSure™ in appendectomy, with or without acute inflammatory process, and to compare with simple ligature and conventional therapy. Methods: A total of 30 rabbits (Oryctolagus cuniculus) randomly allocated in two groups, group A and B, of 15 animals each were used. The group A without acute appendicitis and the group B with acute appendicitis were submitted to appendectomy. After, the groups were subdivided into three groups, each group containing five rabbits submitted to simple ligature, conventional therapy and application of LigaSure™. We assessed macroscopic and microscopy parameters of appendiceal stump and operative wound. Results: The group with acute appendicitis that LigaSure™ was applied had fibrosis in 100% of animals, as well as in the other operative techniques used. It suggested that application of LigaSure™ is efficient as other techniques used in healing of appendiceal stump. Conclusions: The application of LigaSure™ induces the formation of fibrosis in the appendiceal stump. The technique proved efficacy to induce enough fibrous tissue to obstruct leakage of enteric content.