The aim of this paper is to present a database of isolated communities (CENISO) with high prevalence of genetic disorders or congenital anomalies in Brazil. We used two strategies to identify such communities: (1) a systematic literature review and (2) a “rumor strategy” based on anecdotal accounts. All rumors and reports were validated in a stepwise process. The bibliographical search identified 34 rumors and 245 rumors through the rumor strategy, and 144 were confirmed. A database like this one presented here represents an important tool for the planning of health priorities for rare diseases in low- and middle-income countries with large populations.
CITATION STYLE
Cardoso, G. C., de Oliveira, M. Z., Paixão-Côrtes, V. R., Castilla, E. E., & Schuler-Faccini, L. (2019). Clusters of genetic diseases in Brazil. Journal of Community Genetics, 10(1), 121–128. https://doi.org/10.1007/s12687-018-0369-1
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