Throughout their lifetime RNA molecules interact with a variety of RNA-binding proteins (RBPs). RBPs control gene expression by regulating splicing, polyadenylation, editing, transport, stability, and translation of RNA. There are ~1500 RBPs encoded by the human genome and recent studies have detected ~1100 proteins directly interacting with polyadenylated RNA. Identifying the RNAs bound by RBPs will continue to provide important insights into the regulation of gene expression.
CITATION STYLE
Wessels, H. H., Hirsekorn, A., Ohler, U., & Mukherjee, N. (2016). Identifying rbp targets with rip-seq. In Methods in Molecular Biology (Vol. 1358). Humana Press Inc. https://doi.org/10.1007/978-1-4939-3067-8_9
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