Profile And Treatment Steven Johnson Syndrome Patients In Inpatient Kemuning I And II RSUD DR. Soetomo Period 2011-2015

Abstract

Background: Steven Johnson Syndrome (SJS) is uncommon but potentially life threatening disease. SJS is Severe Cutaneous Adverse Reaction (SCAR). SJS is mostly caused by drugs and related with morbidity and mortality. Some researches have been published, but there was no standard for SJS’ treatment. The aim of this study is to present epidemiological features, aetiologies, clinical outcomes, medical histories, and treatments of SJS in Inpatient Unit Kemuning I and II RSUD Dr. Soetomo 2011-2015.Methods: This research used retrospective study which use secondary data collected from medical records. All of patients in Inpatient Kemuning I and II RSUD Dr. Soetomo from year 2011-2015 who diagnosed SJS were included in this research.Result: There were 29 medical records and consist of 23 woman and 6 man with the diagnosis of SJS found in 2011-2015. Most patients aged 25-44 years old. Most clinical history was fever. Drug which is expected to be the most cause of SJS is amoxicillin. There was no family history of SJS in all patients. Mucosa that was involved the most was eyes and mouth. Systemic treatments for patients were corticosteroid. The average duration of treatment was 15,88 day. None of the patients died.Conclusion: Females were more than males. The main systemic therapy in Inpatient Kemuning I dan II RSUD Dr. Soetomo is intravenous cortiosteroid and no patients died.