Combined T and B cell immunodeficiencies

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Abstract

The immune system is divided into humoral and cellular mechanisms. B cells are known for their role in humoral immunity by secreting antibodies against various pathogens, and T cells are responsible for cell-mediated immunity by killing intracellular organisms. T cells are also necessary in the maturation of B cells into antibody secreting plasma cells.

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Bonilla, F. A., Barlan, I. B., Aydiner, E., Al-Herz, W., Eibl, M. M., Espanol, T., … Aghamohammadi, A. (2012). Combined T and B cell immunodeficiencies. In Clinical Cases in Primary Immunodeficiency Diseases: A Problem-Solving Approach (pp. 77–112). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-31785-9_2

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