Treatment of stiff‐man syndrome with intravenous immune globulin

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Abstract

Objective. To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff‐man syndrome (SMS). Methods. An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids. Results. All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function. Conclusion. IVIG may be useful for the treatment of SMS. Copyright © 1994 American College of Rheumatology

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Karlson, E. W., Sudarsky, L., Ruderman, E., Pierson, S., Scott, M., & Helfgott, S. M. (1994). Treatment of stiff‐man syndrome with intravenous immune globulin. Arthritis & Rheumatism, 37(6), 915–918. https://doi.org/10.1002/art.1780370621

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