2′-Methyl-2′-nitro-1′-phenyl-2′,3′,5′, 6′,7′,7a′-hexahydrospiro[indoline-3,3′-1′H- pyrrolizin]-2-one

Abstract

The title compound, C21H21N3O3, was synthesized by a multi-component 1,3-dipolar cyclo-addition of azomethine ylide, derived from isatin and proline by a deca-rboxylative route, and (E)-1-phenyl-2-nitro-propene. In the mol-ecule, the spiro junction links a planar oxindole ring and a pyrrolidine ring in an envelope conformation. The mol-ecular packing is stabilized by an inter-molecular N - H⋯N inter-action of the oxindole and pyrrolizidine rings.