ProteinChip® clinical proteomics: Computational challenges and solutions

137Citations
Citations of this article
16Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

ProteinChip® technology, a suite of analytical tools that includes retentate chromatography, on-chip protein characterization, and multivariate analysis, allows researchers to examine patterns of protein expression and modification. Based on the surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) approach (17), ProteinChip technology has been pioneered by researchers at Ciphergen Biosystems (Fremont, CA, USA), as well as by users of Ciphergen's commercial embodiment of this technology, the ProteinChip Biomarker System. This report will begin with a background of the technology and describe its applications in clinical proteomics and will then conclude with a discussion of tools and strategies to mine the large amounts of data generated during the course of a typical clinical proteomics study.

Cite

CITATION STYLE

APA

Fung, E. T., & Enderwick, C. (2002). ProteinChip® clinical proteomics: Computational challenges and solutions. BioTechniques, 32(3 SUPPL.). https://doi.org/10.2144/mar0205

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free