Gamma-Ray sterilization effects in silica nanoparticles/γ-APTES nanocomposite-based pH-sensitive polysilicon wire sensors

11Citations
Citations of this article
20Readers
Mendeley users who have this article in their library.

Abstract

In this paper, we report the γ-ray sterilization effects in pH-sensitive polysilicon wire (PSW) sensors using a mixture of 3-aminopropyltriethoxysilane (γ-APTES) and polydimethylsiloxane (PDMS)-treated hydrophobic fumed silica nanoparticles (NPs) as a sensing membrane. pH analyses showed that the γ-ray irradiation-induced sensitivity degradation of the PSW pH sensor covered with γ-APTES/silica NPs nanocomposite (γ-APTES+NPs) could be restored to a condition even better than prior to γ-ray irradiation by 40-min of post-sterilization room-temperature UV annealing. We found that the trapping charges caused by γ-ray sterilization primarily concentrated in the native oxide layer for the pH sensor covered with γ-APTES, but accumulated in the γ-APTES+NPs layer for the γ-APTES+NPs-covered sensor. It is believed that mixing the PDMS-treated silica NPs into γ-APTES provides many γ-APTES/SiO2 interfaces for the accumulation of trapping charges and for post-sterilization UV oxidation, thus restoring γ-ray-induced sensor degradation. The PDMS-treated silica NPs not only enhance the sensitivity of the pH-sensitive PSW sensors but are also able to withstand the two-step sterilization resulting from γ-ray and UV irradiations. This investigation suggests γ-ray irradiation could be used as a highly-efficient sterilization method for γ-APTES-based pH-sensitive biosensors. © 2011 by the authors; licensee MDPI, Basel, Switzerland.

Cite

CITATION STYLE

APA

Lin, J. J., & Hsu, P. Y. (2011). Gamma-Ray sterilization effects in silica nanoparticles/γ-APTES nanocomposite-based pH-sensitive polysilicon wire sensors. Sensors, 11(9), 8769–8781. https://doi.org/10.3390/s110908769

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free