CD146 detection with real-time total internal reflection imaging ellipsometry

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Abstract

Biosensor with the total internal reflection imaging ellipsometry (TIRIE) uses an evanescent wave as optical probe to monitor bio-molecular interaction with a high sensitivity due to its property of phase sensitive. Here, the biosensor is applied for a quantitative detection of CD146 with concentrations of 0.1 to 100 ng/mL in order to realize a high sensitive quantitative detection. Moreover, the regression curve between the signal of biosensor (y) and CD146 concentration (x.. lnC+2.4) is deduced as a linear y=1.0544x+0.7839. © 2009 Springer-Verlag.

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Liu, L., Niu, Y., Meng, Y. H., Chen, S., Yan, X. Y., & Jin, G. (2009). CD146 detection with real-time total internal reflection imaging ellipsometry. In IFMBE Proceedings (Vol. 25, pp. 34–36). Springer Verlag. https://doi.org/10.1007/978-3-642-03887-7_10

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