Breast angiosarcoma

Abstract

OBJECTIVE: To report the case of a female with Mammary Angiosarcoma. SETTING: Breast Unit of Oncology Service from Hospital General de México. CASE REPORT: A 28 year old female patient was noted to have a left painless breast mass with reddish-violaceous macular lesions in the overlaying skin in upper quadrants, which she had initially discovered 2 years previously. The patient described a progressive breast enlargement. Mammography showed dense tissue without focal mass. A contrast-enhanced Magnetic Resonance of left breast was performed, and 10.5 x 8.5 cm enhancing vascular mass with irregular borders that occupied the entire superior portion of the breast was identified, the mass extended to the pectoral fascia but no evidence of muscle invasion. An incisional Biopsy of the breast mass was performed and the biopsy was interpreted as low grade Mammary Angiosarcoma. Left Simple Mastectomy with partial pectoral resection was performed; and final histopathologic result was intermediate grade Mammary Angiosarcoma. Immunohistochemistry was positive for Factor VIII, Anti Ulex Europeaus and CD 31. CONCLUSION: High index suspect is mandatory for an opportune diagnosis and treatment of Angiosarcoma. Magnetic resonance has a potential role in guiding clinical management.