Numerous growth factors have been implicated in glioma angiogenesis. This chapter focuses on the role of scatter factor/hepatocyte growth factor, fibroblast growth factor, platelet-derived growth factor and transforming growth factor beta. We review the expression pattern of these factors in gliomas, their functional contribution to tumor angiogenesis - also in relation to vascular endothelial growth factor, and the effects resulting from their inhibition or overexpression in gliomas in vivo.
CITATION STYLE
Lamszus, K., Heese, O., & Westphal, M. (2004). Angiogenesis-related growth factors in brain tumors. Cancer Treatment and Research. https://doi.org/10.1007/978-1-4419-8871-3_12
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