Melanoma antibody approved

Abstract

The March 25 US Food and Drug Administration (FDA) approval of Bristol-Myers Squibb's Yervoy (ipilimumab) for metastatic melanoma was expected, but the breadth of the approval was not. Yervoy, a human monoclonal antibody targeting cytotoxic T-lymphocyte activator-4 (CTLA4) developed by the New York–based company, is the first agent to prolong survival in a phase 3 trial in metastat…