Interleukin 37 (IL-37) is a new member of the IL-1 family which all have a similar β-barrel structure. Since its discovery, IL-37 has been studied extensively in immunological field. It has been established that IL-37 possesses anti-inflammatory characteristics both in innate immune response as well as in acquired immune responses by downregulating pro-inflammatory molecules. This review will discuss the role of IL-37 in immunological processes and neoplastic pathogenesis.
CITATION STYLE
Ding, V. A., Zhu, Z., Xiao, H., Wakefield, M. R., Bai, Q., & Fang, Y. (2016, July 1). The role of IL-37 in cancer. Medical Oncology. Humana Press Inc. https://doi.org/10.1007/s12032-016-0782-4
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