Laser Interaction with Biological Material: Mathematical Modeling (Biological and Medical Physics, Biomedical Engineering)

Abstract

This book covers the principles of laser interaction with biological cells and tissues of varying degrees of organization. The problems of biomedical diagnostics are considered. Scattering of laser irradiation of blood cells is modeled for biological structures (dermis, epidermis, vascular plexus). An analytic theory is provided which is based on solving the wave equation for the electromagnetic field. It allows the accurate analysis of interference effects arising from the partial superposition of scattered waves. Treated topics of mathematical modeling are: optical characterization of biological tissue with large-scale and small-scale inhomogeneities in the layers, heating blood vessel under laser irradiation incident on the outer surface of the skin and thermo-chemical denaturation of biological structures at the example of human skin. Methods describing the interaction of laser radiation with biological tissues -- Overview of theoretical approaches to the analysis of light scattering -- Modeling of optical characteristics of spherical particles in the optical resonator cavity -- Mathematical models of the interaction of laser radiation with turbid media -- Study of the optical characteristics of a biotissue with large-scale imhomogeneities -- Light scattering by dielectric bodies of irregular shape in a layered medium -- Modeling of the optical characteristics fibrillar structure -- Study of optical properties of biotissues by the intracavity laser spectroscopy method -- Study of the optical characteristiscs of thin layer of the biological sample -- Simulation of the thermal processes.