Mass spectrometric characterization in protein therapeutics discovery

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Abstract

With advances in recombinant DNA and hybridoma technologies, including chimerization and humanization, which allow customized proteins to be produced in large quantities, pharmaceutical applications of proteins as human therapeutics have expanded rapidly in the last 30 years.

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Mo, J., Tymiak, A. A., & Chen, G. (2013). Mass spectrometric characterization in protein therapeutics discovery. In Characterization of Protein Therapeutics using Mass Spectrometry (Vol. 9781441978622, pp. 163–205). Springer US. https://doi.org/10.1007/978-1-4419-7862-2_5

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