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Reaction of cimetidine with Fenton reagent

  • ZBAIDA S
  • KARIV R
  • FISCHER P
  • et al.
European Journal of Biochemistry (1986) 154(3) 603-605
DOI: 10.1111/j.1432-1033.1986.tb09441.x
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Abstract

Cimetidine sulfoxide, N ‐desmethylcimetidine, N ‐desmethylcimetidine sulfoxide, cimetidine guanylurea, and the 5‐hydroxymethylimidazole derivative of cimetidine sulfoxide were isolated from the reaction of cimetidine with Fenton reagent. The product distribution from the reaction of cimetidine with Fenton reagent clearly simulates the metabolism of cimetidine by the mixed‐function oxidase.

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ZBAIDA, S., KARIV, R., FISCHER, P., SILMAN‐GREENSPAN, J., & TASHMA, Z. (1986). Reaction of cimetidine with Fenton reagent. European Journal of Biochemistry, 154(3), 603–605. https://doi.org/10.1111/j.1432-1033.1986.tb09441.x

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