Why so many sperm cells?

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Abstract

A key limiting step in fertility is the search for the oocyte by spermatozoa. Initially, there are tens of millions of sperm cells, but a single one will make it to the oocyte. This may be one of the most severe selection processes designed by evolution, whose role is yet to be understood. Why such a huge redundancy is required and what does that mean for the search process? we discuss here these questions and consequently new lines of interdisciplinary research needed to find possible answers.

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Reynaud, K., Schuss, Z., Rouach, N., & Holcman, D. (2015). Why so many sperm cells? Communicative and Integrative Biology, 8(3). https://doi.org/10.1080/19420889.2015.1017156

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