Facile synthesis of diverse multisubstituted ortho-silylaryl triflates via CH borylation

Abstract

Diverse multisubstituted ortho-silylaryl triflates were efficiently synthesized from simple ortho-silylaryl triflates via iridium-catalyzed regioselective CH borylation and subsequent deborylative functionalizations. An azidoaryne precursor synthesized by this method served as a useful bis-reactive platform molecule, thus demonstrating the utility of the method for preparing diverse aromatic compounds.