A colorimetric and fluorescent pH probe 1-(4-methylphenyl)-3-(4-dimethylaminophenyl) acrylketone (MDAK) was facilely prepared. The probe exhibited strong pH-dependent behavior and responded linearly and rapidly to minor pH fluctuations within the range of 1.53-3.96. In addition, MDAK displayed a notably large Stokes shift of 121 nm. MDAK possessed a highly selective response to H+ over other metal ions, amion acids and displayed good photostability and excellent reversibility. Furthermore, it can be applied to visualize extreme acidity in E. coli cells.
CITATION STYLE
Chao, J., Song, K., Wang, H., Li, Z., Zhang, Y., Yin, C., … Zhang, T. (2017). A colorimetric and fluorescent pH probe for imaging in E. coli cells. RSC Advances, 7(2), 964–970. https://doi.org/10.1039/c6ra24885c
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