Studies on the biosynthesis of ralfuranones in Ralstonia solanacearum

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Abstract

Ralfuranones, aryl-furanone secondary metabolites, are involved in the virulence of Ralstonia solanacearum in solanaceous plants. Ralfuranone I (6) has been suggested as a biosynthetic precursor for other ralfuranones; however, this conversion has not been confirmed. We herein investigate the biosynthesis of ralfuranones using feeding experiments with ralfuranone I (6) and its putative metabolite, ralfuranone B (2). The results obtained demonstrated that the biosynthesis of ralfuranones proceeded in enzymatic and non-enzymatic manners.

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Kai, K., Ohnishi, H., Kiba, A., Ohnishi, K., & Hikichi, Y. (2016). Studies on the biosynthesis of ralfuranones in Ralstonia solanacearum. Bioscience, Biotechnology and Biochemistry, 80(3), 440–444. https://doi.org/10.1080/09168451.2015.1116931

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