Racional e desenho do registro brasileiro de implante de bioprótese aórtica por cateter

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Abstract

Background: Surgical replacement of the aortic valve is the therapy of choice for patients with severe aortic stenosis. However, the surgical risk increases dramatically as age advances and with the association of comorbidities. Recently, transcatheter aortic valve implantation has been introduced in Brazil. Therefore, it was important to create a national registry to determine the outcomes of this procedure in our country. The rationale and design of the Brazilian Transcatheter Aortic Valve Implantation Registry is described. Methods: This is a multicenter prospective registry, including 200 patients with symptomatic aortic valve stenosis and high surgical risk submitted to transcatheter aortic valve implantation in Brazilian institutions. The primary endpoint of the study is all cause mortality at 30 days, 12 and 24 months. Secondary endpoints, among others, are: 1) technical success of transcatheter valve implantation; 2) cardiovascular mortality at 30 days, 12 and 24 months; 3) composite safety endpoint at 30 days; and 4) composite efficacy endpoint at 12 and 24 months. Conclusions: The nacional permitirá avaliar os defechos do implante percutâneo de biopróteses aórticas em nosso meio. DESCRITORES: Estenose da valva aórtica. Implante de prótese de valva cardíaca. Bioprótese. Cateteres. analysis of the results of this national registry will enable us to evaluate the outcomes of transcatheter aortic valve implantation in our country. © 2011 Sociedade Brasileira de Hemodinãmica e Cardiologia Intervencionista.

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de Brito Júnior, F. S., Siqueira, D., Sarmento-Leite, R., Carvalho, L. A., Neto, P. A. L., Mangione, J. A., … Sousa, J. E. (2011). Racional e desenho do registro brasileiro de implante de bioprótese aórtica por cateter. Revista Brasileira de Cardiologia Invasiva, 19(2). https://doi.org/10.1590/s2179-83972011000200008

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