Abstract
By mRNA differential display in mouse hearts, lysyl oxidase (Lox), a key enzyme catalyzing cross-links in elastin and collagens, was found to be up-regulated between embryonic days 11 (Ell) and 13 (E13). This was confirmed by semiquantitative RT-PCR. We analyzed its spatio-temporal expression pattern by in situ hybridization in regard to the development of myocardial cells, endocardial cushion tissue, aortic arch vessels, and epicardium. © 2003 Wiley-Liss, Inc.
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Tsuda, T., Pan, T. C., Evangelisti, L., & Chu, M. L. (2003). Prominent expression of lysyl oxidase during mouse embryonic cardiovascular development. Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, 270(2), 93–96. https://doi.org/10.1002/ar.a.10002
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