Advances in rapid detection and antimicrobial susceptibility tests

Abstract

The rise of antibiotic resistance is an emerging problem of the millennium. Clinical microbiology plays an important role in combating the problem by facilitating diagnostics and therapeutics thus managing infection in patients. Diagnostic failures are a major limiting factor during bacterial infection that causes inappropriate use of antibiotics, delay in start up of treatment and decrease in the survival rate during septic conditions. Thus rapid and reliable detection is highly relevant during such bacterial infections and also at the time of disease outbreak as many such pathogens can be used as biothreat agents or bioweapons affecting human health and posing risk to national security. The importance of various methods for fast pathogen detection and antimicrobial susceptibility determination is highlighted. These methods have the potential to provide very precise and rapid ways for bacterial screening and identifying the correct antibiotics to cure infection.