In Vivo selection of rifamycin-resistant clostridium difficile during rifaximin therapy

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Abstract

We report the selection of Clostridium difficile resistant to the rifamycin class of antibiotics in a patient within 32 h of receiving rifaximin for the treatment of recurrent C. difficile diarrhea. Resistance was associated with single nucleotide substitutions within rpoB. Copyright © 2012, American Society for Microbiology. All Rights Reserved.

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Carman, R. J., Boone, J. H., Grover, H., Wickham, K. N., & Chen, L. (2012). In Vivo selection of rifamycin-resistant clostridium difficile during rifaximin therapy. Antimicrobial Agents and Chemotherapy, 56(11), 6019–6020. https://doi.org/10.1128/AAC.00974-12

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