Lipidomics: Metabolic analysis of phospholipids

Abstract

6. Conclusions: At present, we are attempting to develop basic analytical methods, a database, and search tools for lipidomics, i.e., metabolomics focusing on lipids. Further, in order to develop in new analytical methods and identification tools, we believe that our efforts will be successfuly only through collaboration with numerous cooperating researchers and application personnel of MS manufacturers. Analysis by ESI-MS can be applied to elucidate lipid mediators in the cells as well as for the purposes of detection and quantification, and for localization in the cells of minor lipid metabolites. Bioinformatics studies based on both data of proteome of enzymes and receptors, as well as metabolome of lipids, will make it possible to acquire new knowledge on the metabolic and signaling pathways of lipid metabolism.