Source Differences in ERP Components Between Pain and Tactile Processing

Abstract

It is a promising method to use intra-epidermal electrical stimulation (IES) as a practical stimulation for nociceptive pain study. There is a question on whether IES involve other sensory receptors, e.g. tactile. This paper is to investigate whether IES could selectively activate Aδ-nociceptors during an oddball paradigm from the perspective of cortical sources by using sLORETA, and moreover, the source differences between nociceptive and non-nociceptive processing. The results provide further evidences to support that IES could effectively activate Aδ-nociceptors selectively.