Kawasaki disease is the most common acute systemic vasculitis of unknown etiology in children [1] and can cause inflammation of the coronary arteries leading to aneurysms. Tenascin-C, an extracellular matrix protein, and c-Jun N-terminal kinase (JNK), an intracellular signaling protein, are known to be associated with inflammation and tissue remodeling [2, 3]. The purpose of this study was to demonstrate tenascin-C and JNK might be involved in tissue remodeling in a Candida albicans-induced murine model of aneurysm.
CITATION STYLE
Yoshikane, Y., Koga, M., Cho, T., Imanaka-Yoshida, K., Yamamoto, Y., Hashimoto, J., … Hirose, S. (2016). Tissue remodeling in vascular wall in Kawasaki disease-related vasculitis model mice. In Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology (pp. 241–242). Springer Japan. https://doi.org/10.1007/978-4-431-54628-3_33
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