Iodic acid (HIO3)

Abstract

(A) Patil et al. reported a useful method for the iodination of hydroxy aryl ketones; they showed a variety of ortho-hydroxy-substituted aromatic carbonyl compounds which were selectively iodinated in 81-87% yield by using iodine and iodic acid. (B) Zolfigol and co-workers have used HIO3 and NaNO2 in the presence of wet SiO2 as a nitrosating agent for the effective and selective nitrosation of secondary amines under mild and heterogeneous conditions in good yields. (C) Shirini et al. reported a simple and efficient method for the oxidation of thiols to disulfides and sulfides to sulfoxides in 87-95% yield using aqueous HIO3 at room temperature. Also Lakouraj and co-workers have explained the utility of HIO3 for oxidation of sulfides to sulfoxides in the presence of wet SiO2 under solvent-free conditions. (D) Ketoximes and aromatic aldoximes are converted to the corresponding carbonyl compounds with HIO3 under mild and heterogeneous conditions in CH2Cl2 at room temperature in 67-97% yields. Also deoximation and dehydrazonation have been reported using HIO3 in the presence of wet SiO2 under solvent-free conditions. (E) A variety of aldehydes and ketones were readily and selectively transformed to 1,3-saturated aldehydes and ketones with HIO3 and I2O5 at 45-65 °C in good yields. (F) Hashemi and Akhbari showed the conversion of a variety of aromatic amines into their corresponding quinines under microwave irradiation. (G) A variety of thioacetals and thioketals were deprotected to the corresponding carbonyl compounds with HIO3 in the presence of wet SiO2 at room temperature under solvent-free conditions. © Georg Thieme Verlag Stuttgart.