Morphogenesis model for systematic simulation of forms’ co-evolution with constraints: Application to mitosis

Abstract

We present a new approach to understand forms’ emergence in a cellular system. We set the hypothesis that beyond the influence of mechanical forces and gene expression, constraints applied to the cells over time play a key role in the acquisition of specific shape. We consider that these constraints are the fundamental principles and basic cause of morphogenesis. In our model, it’s due to these constraints that cells choose a particular direction while dividing, migrate or die. Our approach of morphogenesis based on constraints has been used to get effectively for a given form all possible evolutions by growth at latter times. Such work ensures to do some pattern prediction.