Antibacterial Activities of Some Medicated Soaps on Selected Human Pathogens

Abstract

Twelve medicated soaps: Crusader, Septol, Carat, 14 days, Funbact, Lifebouy, Safeguard, Tetmosol, TCP, Dettol, Delta and Antigal were investigated for their antibacterial activities against Staphylococcus aureus and Escherichia coli. Two cloth washing soaps (Key and Truck) were used as control. Identification of the bacterial species was by standard microbiological techniques which included colonial examination, Gram staining and biochemical testing. Minimum inhibitory and minimum bactericidal activities of the soaps were determined by disc-agar diffusion method. Profloxacin was employed as a positive control antibiotic. Crusader soap had the highest antibacterial activity (25 mm, against Staphylococcus aureus) while Antigal exhibited the least zone of inhibition (9 mm against Staphylococcus aureus). Significant differences (P<0.05) were observed on the different concentrations of soap preparations used in the work. Staphylococcus aureus was very sensitive to most of the antibacterial soaps used, while Escherichia coli showed higher resistance to the soaps. The medicated soaps analysed have bacteriostatic and bacteriocidal effects on the test pathogens while complete resistance was shown by some of the test isolates even at higher concentrations of the soap preparations used. The cloth washing soaps had no antibacterial effect on the tested pathogens. The use of medicated soaps is thus recommended in homes, schools, offices and hospitals as a way of minimizing or stopping infections that are hitherto spread through the hands.