Flexible Nanopipettes for Minimally Invasive Intracellular Electrophysiology In Vivo

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Abstract

Jayant et al. introduce flexible nanopipettes for minimally invasive intracellular electrical recordings in vivo and, in conjunction with two-photon imaging, show that these electrodes permit targeted recordings from both somata and thin dendrites. In addition, flexible nanopipettes facilitate targeted recordings across cortical depth and under different brain states.

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Jayant, K., Wenzel, M., Bando, Y., Hamm, J. P., Mandriota, N., Rabinowitz, J. H., … Yuste, R. (2019). Flexible Nanopipettes for Minimally Invasive Intracellular Electrophysiology In Vivo. Cell Reports, 26(1), 266-278.e5. https://doi.org/10.1016/j.celrep.2018.12.019

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