Discovery of neuritogenic compound classes inspired by natural products

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Abstract

Neuroactive! An enantioselective, catalytic synthesis strategy provides rapid access to natural-product-inspired classes of neuritogenic compounds (see scheme). The goal is to find interesting chemical probes to shed light on neurodevelopmental processes and foster a better understanding of the complex biology and physiology of neuronal development and related neurodegenerative disorders. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Dakas, P. Y., Parga, J. A., Höing, S., Schöler, H. R., Sterneckert, J., Kumar, K., & Waldmann, H. (2013). Discovery of neuritogenic compound classes inspired by natural products. Angewandte Chemie - International Edition, 52(36), 9576–9581. https://doi.org/10.1002/anie.201302045

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